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Development of an algorithm to predict HIV-1 tropism from V3 loop sequence for BF subtype
(A2B2C, 2015-10-14)
HIV tropism can be X4 or R5 according to the co-receptor usage for viral entry into CD4+ T cells. This interaction involves the V3 loop region of viral glycoprotein gp120, coded in the env gene. The determination of viral ...
Improved pipeline to determine HIV-1 tropism for pyrosequencing reads using geno2pheno
(A2B2C, 2015-10-14)
The gp120 HIV-1 protein is responsible for the use of different co-receptors when HIV enters host cells. Bioinformatics tools such as Geno2pheno can predict viral tropism based on the sequence of a small region of gp120 ...